Independent peptide education · Evidence annotated · Research use information
Peptide Library / SS-31

SS-31 Research Guide

Mitochondria-targeting tetrapeptide also known as elamipretide

Human clinical trials
ClassificationSingle Peptide
Evidence tierHuman clinical trials
Research statusEducational reference
01 · At a glance

Overview

SS-31 is included in this independent research library to separate what has been demonstrated from what remains theoretical. The evidence, regulatory status and terminology vary substantially by compound, so claims should be read in the context of the cited literature.

Dosing & reconstitution guide

SS-31 suggested dosing guide

A concise reference to the dosing ranges most often used in approved labeling, clinical research, or published research discussions. Evidence strength is shown so established dosing is not confused with experimental protocol.

Clinical-trial
Suggested starting range0.01–0.25 mg/kg studied
Typical reference rangeTrial specific
FrequencyOnce daily in many trials
TimingConsistent daily timing
Typical durationVaried by trial
RouteSubcutaneous injection

Titration and protocol notes

Use the exact clinical-trial protocol; no general-purpose regimen is established.

Annotated dosage protocol

Each row explains what the dosage represents. Read it with the evidence badge above: labeled doses, clinical-trial doses, and commonly discussed research amounts do not carry equal clinical weight.

PhaseDoseScheduleWhat this dosage means
Starting phase0.01–0.25 mg/kg studiedOnce daily in many trialsThe entry dose or lowest studied range, used before any protocol-directed increase.
Treatment rangeTrial specificConsistent daily timingThe range used after initiation. The applicable dose depends on the labeled indication or study design.
Duration / reassessmentVaried by trialReassess before continuingUse the exact clinical-trial protocol; no general-purpose regimen is established. Dose changes should never be inferred from vial size or convenient syringe units.

SS-31 reconstitution example

This worked example uses a 5 mg vial, 2 mL of diluent, and a 5,000 mcg reference amount.

Vial strength5 mg
Diluent added2 mL
Concentration2.5 mg/mL
Example draw2 mL / 200 units
How this example is calculated: 5 mg ÷ 2 mL = 2.5 mg/mL. The 5,000 mcg reference amount equals 5 mg. That produces a 2 mL draw, or 200 units on a U-100 syringe.

Syringe units assume a U-100 syringe. Always verify the vial label, syringe type, formulation, and arithmetic independently.

Safety, handling, and storage
  • Suggested ranges are educational summaries, not individualized prescriptions.
  • FDA-labeled regimens apply only to the approved product, indication, and delivery system.
  • For experimental compounds, human safety, purity, and effective dosing may be unknown.
  • Follow product-specific sterility, storage, and beyond-use instructions; do not use damaged or contaminated material.
Live concentration math

SS-31 calculator

Enter your laboratory values to calculate concentration, draw volume, syringe units, and portions per vial.

Runs in your browser
Concentration2.5 mg/mL
Draw volume2 mL
On the syringe200 units
Portions per vial1

Deterministic arithmetic for laboratory documentation only. This tool does not select a dose, provide a protocol, or replace qualified medical or laboratory guidance.

02 · How it is studied

Mechanism and research rationale

Designed to associate with cardiolipin in the inner mitochondrial membrane and studied for effects on mitochondrial structure and bioenergetics.

Mitochondrial function

Cardiac research

Cellular energetics

03 · Interpretation

Key facts

  • Evidence tier: Human clinical trials.
  • Research status and regulatory status are not interchangeable.
  • This page is an educational reference and does not provide personal medical instructions.
04 · Editorial annotations

What to keep in mind

Editorial note: distinguish peer-reviewed findings from supplier or community claims.
Evidence note: study design, species, route and formulation can materially change interpretation.
05 · Sources

References and evidence indexes

  1. PubMed search: SS-31
  2. ClinicalTrials.gov search
Research product

Looking for SS-31?

View the corresponding SS-31 research product, specifications, and available documentation from Novatherix Laboratories.

View at Novatherix →

External catalog link. For qualified laboratory and research use only.

Research notice: This guide is educational and not medical advice. It does not diagnose, treat, prescribe, or recommend personal use.